Gene copy number and function of the APL1 immune factor changed during Anopheles evolution

Gene copy number and function of the APL1 immune factor changed during Anopheles evolution

Abstract Background The recent reference genome assembly and annotation of the Asian malaria vector Anopheles stephensi detected only one gene encoding the leucine-rich repeat immune factor APL1, while in the Anopheles gambiae and sibling Anopheles coluzzii, APL1 factors are encoded by a family of t...

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Bibliographic Details
Main Authors: Christian Mitri, Emmanuel Bischoff, Karin Eiglmeier, Inge Holm, Constentin Dieme, Emma Brito-Fravallo, Abbasali Raz, Sedigheh Zakeri, Mahdokht I. K. Nejad, Navid D. Djadid, Kenneth D. Vernick, Michelle M. Riehle
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Parasites & Vectors
Subjects:
Mosquito
Insect immunity
Gene family
Gene essentiality
Gene neofunctionalization
Online Access:https://doi.org/10.1186/s13071-019-3868-y

Internet

https://doi.org/10.1186/s13071-019-3868-y

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