CHOP Pro-Apoptotic Transcriptional Program in Response to ER Stress is Hacked by Zika Virus

CHOP Pro-Apoptotic Transcriptional Program in Response to ER Stress is Hacked by Zika Virus

Zika virus (ZIKV) is an emerging mosquito-borne flavivirus considered as a threat to human health due to large epidemics and serious clinical outcomes such as microcephaly in new-borns. Like all flaviviruses, ZIKV relies on the cellular machinery to complete its viral cycle, with the endoplasmic ret...

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Bibliographic Details
Main Authors: Jonathan Turpin, Daed El-Safadi, Grégorie Lebeau, Etienne Frumence, Philippe Desprès, Wildriss Viranaïcken, Pascale Krejbich-Trotot
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
Zika virus
ER stress
unfolded protein response
apoptosis
CHOP
Online Access:https://www.mdpi.com/1422-0067/22/7/3750

Internet

https://www.mdpi.com/1422-0067/22/7/3750

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