Balance between the two kinin receptors in the progression of experimental focal and segmental glomerulosclerosis in mice

Balance between the two kinin receptors in the progression of experimental focal and segmental glomerulosclerosis in mice

Focal and segmental glomerulosclerosis (FSGS) is one of the most important renal diseases related to end-stage renal failure. Bradykinin has been implicated in the pathogenesis of renal inflammation, whereas the role of its receptor 2 (B2RBK; also known as BDKRB2) in FSGS has not been studied. FSGS...

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Bibliographic Details
Main Authors: Rafael Luiz Pereira, Raphael José Ferreira Felizardo, Marcos Antônio Cenedeze, Meire Ioshie Hiyane, Ênio José Bassi, Mariane Tami Amano, Clarice Sylvia Taemi Origassa, Reinaldo Correia Silva, Cristhiane Fávero Aguiar, Sylvia Mendes Carneiro, João Bosco Pesquero, Ronaldo Carvalho Araújo, Alexandre de Castro Keller, Renato C. Monteiro, Ivan Cruz Moura, Alvaro Pacheco-Silva, Niels Olsen Saraiva Câmara
Format: Article
Language:English
Published: The Company of Biologists 2014-06-01
Series:Disease Models & Mechanisms
Subjects:
Focal and segmental glomerulosclerosis
Bradykinin receptors
Inflammation
Podocyte
Fibrosis
Online Access:http://dmm.biologists.org/content/7/6/701

Internet

http://dmm.biologists.org/content/7/6/701

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