Mutations in genes affecting DNA methylation enhances responses to decitabine in patients with myelodysplastic syndrome

Background/Aims In this study, we tested whether mutations in the methylation pathway genes ten-eleven-translocation 2 (TET2) and DNA methyltransferase gene 3A (DNMT3A) improve the responses of patients with myelodysplastic syndrome (MDS) to decitabine. Methods We retrospectively sequenced the TET2...

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Bibliographic Details
Main Authors: Hyun Ae Jung, Chul Won Jung, Jun Ho Jang
Format: Article
Language:English
Published: The Korean Association of Internal Medicine 2021-03-01
Series:The Korean Journal of Internal Medicine
Subjects:
Online Access:http://www.kjim.org/upload/pdf/kjim-2019-385.pdf