Maternal infection with Trypanosoma cruzi and congenital Chagas disease induce a trend to a type 1 polarization of infant immune responses to vaccines.

Maternal infection with Trypanosoma cruzi and congenital Chagas disease induce a trend to a type 1 polarization of infant immune responses to vaccines.

BACKGROUND: We previously showed that newborns congenitally infected with Trypanosoma cruzi (M+B+) display a strong type 1 parasite-specific T cell immune response, whereas uninfected newborns from T. cruzi-infected mothers (M+B-) are prone to produce higher levels of proinflammatory cytokines than...

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Bibliographic Details
Main Authors: Nicolas Dauby, Cristina Alonso-Vega, Eduardo Suarez, Amilcar Flores, Emmanuel Hermann, Marisol Córdova, Tatiana Tellez, Faustino Torrico, Carine Truyens, Yves Carlier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2796860?pdf=render

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http://europepmc.org/articles/PMC2796860?pdf=render

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