Treatment Planning and Delivery of Whole Brain Irradiation with Hippocampal Avoidance in Rats.

Despite the clinical benefit of whole brain radiotherapy (WBRT), patients and physicians are concerned by the long-term impact on cognitive functioning. Many studies investigating the molecular and cellular impact of WBRT have used rodent models. However, there has not been a rodent protocol compara...

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Bibliographic Details
Main Authors: C K Cramer, S W Yoon, M Reinsvold, K M Joo, H Norris, R C Hood, J D Adamson, R C Klein, D G Kirsch, M Oldham
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4670078?pdf=render