Recombinant Laminins Drive the Differentiation and Self-Organization of hESC-Derived Hepatocytes

Stem cell-derived somatic cells represent an unlimited resource for basic and translational science. Although promising, there are significant hurdles that must be overcome. Our focus is on the generation of the major cell type of the human liver, the hepatocyte. Current protocols produce variable p...

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Bibliographic Details
Main Authors: Kate Cameron, Rosanne Tan, Wolfgang Schmidt-Heck, Gisela Campos, Marcus J. Lyall, Yu Wang, Baltasar Lucendo-Villarin, Dagmara Szkolnicka, Nicola Bates, Susan J. Kimber, Jan G. Hengstler, Patricio Godoy, Stuart J. Forbes, David C. Hay
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671115003136