Transgenic Chicks Expressing Interferon-Inducible Transmembrane Protein 1 (IFITM1) Restrict Highly Pathogenic H5N1 Influenza Viruses

Transgenic Chicks Expressing Interferon-Inducible Transmembrane Protein 1 (IFITM1) Restrict Highly Pathogenic H5N1 Influenza Viruses

Mammalian cells utilize a wide spectrum of pathways to antagonize the viral replication. These pathways are typically regulated by antiviral proteins and can be constitutively expressed but also exacerbated by interferon induction. A myriad of interferon-stimulated genes (ISGs) have been identified...

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Bibliographic Details
Main Authors: Mohammed A. Rohaim, Mohammad Q. Al-Natour, Mohammed A. Abdelsabour, Rania F. El Naggar, Yahia M. Madbouly, Kawkab A. Ahmed, Muhammad Munir
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
transgenic chickens
chIFITM1
HPAIV H5N1
zoonotic infections
Online Access:https://www.mdpi.com/1422-0067/22/16/8456

Internet

https://www.mdpi.com/1422-0067/22/16/8456

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