Uremic Toxins in the Progression of Chronic Kidney Disease and Cardiovascular Disease: Mechanisms and Therapeutic Targets

Chronic kidney disease (CKD) is a progressive loss of renal function. The gradual decline in kidney function leads to an accumulation of toxins normally cleared by the kidneys, resulting in uremia. Uremic toxins are classified into three categories: free water-soluble low-molecular-weight solutes, p...

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Bibliographic Details
Main Authors: Yong Jin Lim, Nicole A. Sidor, Nicholas C. Tonial, Adrian Che, Bradley L. Urquhart
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/13/2/142