Age-related changes in neuroinflammation and prepulse inhibition in offspring of rats treated with Poly I:C in early gestation

Age-related changes in neuroinflammation and prepulse inhibition in offspring of rats treated with Poly I:C in early gestation

Abstract Background Maternal immune activation (MIA) during gestation can increase the later risk of schizophrenia in adult offspring. Neuroinflammation is believed to underlie this process. Postmortem brain studies have found changes in the neuroimmune systems of patients with schizophrenia. Howeve...

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Bibliographic Details
Main Authors: Shuang Ding, Yunqing Hu, Binbin Luo, Yaqi Cai, Keke Hao, Yongfeng Yang, Yan Zhang, Xiujuan Wang, Minli Ding, Hongxing Zhang, Wenqiang Li, Luxian Lv
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Behavioral and Brain Functions
Subjects:
Maternal immune activation
Schizophrenia
Poly I:C
Microglia
Astrocyte
Online Access:http://link.springer.com/article/10.1186/s12993-019-0154-2

Internet

http://link.springer.com/article/10.1186/s12993-019-0154-2

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