Studies of Non-Protective Autophagy Provide Evidence that Recovery from Therapy-Induced Senescence is Independent of Early Autophagy

Autophagy and senescence, predominant responses that may dictate cell fate after chemotherapy or radiation, often occur in tandem. Cells in states of senescence and/or autophagy are frequently growth arrested. We have previously reported that tumor cells induced into senescence by therapy can re-eme...

Full description

Bibliographic Details
Main Authors: Tareq Saleh, Liliya Tyutyunyk-Massey, Nipa H. Patel, Emmanuel K. Cudjoe, Moureq Alotaibi, David A. Gewirtz
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/4/1427