Taurine Protects C2C12 Myoblasts From Impaired Cell Proliferation and Myotube Differentiation Under Cisplatin-Induced ROS Exposure

Taurine Protects C2C12 Myoblasts From Impaired Cell Proliferation and Myotube Differentiation Under Cisplatin-Induced ROS Exposure

In cancer patients, chemotherapeutic medication induces aberrant ROS (reactive oxygen species) accumulation in skeletal muscles, resulting in myofiber degradation, muscle weakness, and even cachexia, which further leads to poor therapeutic outcomes. Acting as an antioxidant, taurine is extensively u...

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Bibliographic Details
Main Authors: Lin Zhou, Ruohan Lu, Caihua Huang, Donghai Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Molecular Biosciences
Subjects:
taurine
C2C12 myoblasts
myotube differentiation
NMR-based metabolomics
ROS
cisplatin
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.685362/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.685362/full

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