Nucleic acids & endosomal pattern recognition - how to tell friend from foe?

The innate immune system has evolved endosomal and cytoplasmic receptors for the detection of viral nucleic acids as sensors for virus infection. Some of these pattern recognition receptors (PRR) detect features of viral nucleic acids that are not found in the host such as long stretches of double-s...

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Bibliographic Details
Main Authors: Sandra Stephanie Diebold, Eva eBrencicova
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2013.00037/full