Linkage disequilibrium mapping of CHEK2: common variation and breast cancer risk.

Linkage disequilibrium mapping of CHEK2: common variation and breast cancer risk.

BACKGROUND: Checkpoint kinase 2 (CHEK2) averts cancer development by promoting cell cycle arrest and activating DNA repair in genetically damaged cells. Previous investigation has established a role for the CHEK2 gene in breast cancer aetiology, but studies have largely been limited to the rare 1100...

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Main Authors: Kristjana Einarsdóttir, Keith Humphreys, Carine Bonnard, Juni Palmgren, Mark M Iles, Arvid Sjölander, Yuqing Li, Kee Seng Chia, Edison T Liu, Per Hall, Jianjun Liu, Sara Wedrén
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-06-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC1457009?pdf=render

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http://europepmc.org/articles/PMC1457009?pdf=render

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