Age-related changes in the epithelial and stromal compartments of the mammary gland in normocalcemic mice lacking the vitamin D3 receptor.

The vitamin D(3) receptor (VDR) serves as a negative growth regulator during mammary gland development via suppression of branching morphogenesis during puberty and modulation of differentiation and apoptosis during pregnancy, lactation and involution. To assess the role of the VDR in the aging mamm...

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Bibliographic Details
Main Authors: JoEllen Welsh, Lindsay N Zinser, Laurel Mianecki-Morton, Jamie Martin, Susan E Waltz, Howard James, Glendon M Zinser
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3027678?pdf=render