Somatic mutations in exocrine pancreatic tumors: association with patient survival.

Somatic mutations in exocrine pancreatic tumors: association with patient survival.

KRAS mutations are major factors involved in initiation and maintenance of pancreatic tumors. The impact of different mutations on patient survival has not been clearly defined. We screened tumors from 171 pancreatic cancer patients for mutations in KRAS and CDKN2A genes. Mutations in KRAS were dete...

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Bibliographic Details
Main Authors: P Sivaramakrishna Rachakonda, Andrea S Bauer, Huaping Xie, Daniele Campa, Cosmeri Rizzato, Federico Canzian, Stefania Beghelli, William Greenhalf, Eithne Costello, Michaela Schanne, Anette Heller, Aldo Scarpa, John P Neoptolemos, Jens Werner, Markus Büchler, Jörg D Hoheisel, Kari Hemminki, Nathalia Giese, Rajiv Kumar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3614935?pdf=render

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http://europepmc.org/articles/PMC3614935?pdf=render

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