Envelope-specific B-cell populations in African green monkeys chronically infected with simian immunodeficiency virus

Envelope-specific B-cell populations in African green monkeys chronically infected with simian immunodeficiency virus

Infection of African green monkeys with simian immunodeficiency virus is a potential model for HIV vaccine development. Here, Zhang et al. catalogue the immunoglobulin loci present in the genome of these animals, and experimentally study their B-cell response to the viral envelope protein.

Bibliographic Details
Main Authors: Ruijun Zhang, David R. Martinez, Quang N. Nguyen, Justin Pollara, Trina Arifin, Christina Stolarchuk, Andrew Foulger, Josh D. Amos, Robert Parks, Jonathon E. Himes, Minyue Wang, Regina W. Edwards, Ashley M. Trama, Nathan Vandergrift, Lisa Colvin, Ken Dewar, Nikoleta Juretic, Jessica Wasserscheid, Guido Ferrari, Hua-Xin Liao, Sallie R. Permar
Format: Article
Language:English
Published: Nature Publishing Group 2016-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12131

Internet

https://doi.org/10.1038/ncomms12131

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