Implementation of genotype-guided dosing of warfarin with point-of-care genetic testing in three UK clinics: a matched cohort study

Implementation of genotype-guided dosing of warfarin with point-of-care genetic testing in three UK clinics: a matched cohort study

Abstract Background Warfarin is a widely used oral anticoagulant. Determining the correct dose required to maintain the international normalised ratio (INR) within a therapeutic range can be challenging. In a previous trial, we showed that a dosing algorithm incorporating point-of-care genotyping in...

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Bibliographic Details
Main Authors: Andrea L. Jorgensen, Clare Prince, Gail Fitzgerald, Anita Hanson, Jennifer Downing, Julia Reynolds, J. Eunice Zhang, Ana Alfirevic, Munir Pirmohamed
Format: Article
Language:English
Published: BMC 2019-04-01
Series:BMC Medicine
Subjects:
Anticoagulation
Warfarin
Genotype-guided dosing
Pharmacogenetics
Implementation study
Point-of-care
Online Access:http://link.springer.com/article/10.1186/s12916-019-1308-7

Internet

http://link.springer.com/article/10.1186/s12916-019-1308-7

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