The tumor suppressor PTEN regulates motor responses to striatal dopamine in normal and Parkinsonian animals

Phosphatase and Tensin homolog deleted on chromosome 10 (PTEN) is a dual lipid–protein phosphatase known primarily as a growth preventing tumor suppressor. PTEN is also expressed in neurons, and pathways modulated by PTEN can influence neuronal function. Here we report a novel function of PTEN as a...

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Bibliographic Details
Main Authors: Mihaela A. Stavarache, Sergei Musatov, Marlon McGill, Mary Vernov, Michael G. Kaplitt
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:Neurobiology of Disease
Subjects:
AAV
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996115300176