Mechanistic signs of double-barreled structure in a fluoride ion channel

The Fluc family of F− ion channels protects prokaryotes and lower eukaryotes from the toxicity of environmental F−. In bacteria, these channels are built as dual-topology dimers whereby the two subunits assemble in antiparallel transmembrane orientation. Recent crystal structures suggested that Fluc...

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Bibliographic Details
Main Authors: Nicholas B Last, Ludmila Kolmakova-Partensky, Tania Shane, Christopher Miller
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-07-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/18767