Genome-wide identification of ampicillin resistance determinants in Enterococcus faecium.

Enterococcus faecium has become a nosocomial pathogen of major importance, causing infections that are difficult to treat owing to its multi-drug resistance. In particular, resistance to the β-lactam antibiotic ampicillin has become ubiquitous among clinical isolates. Mutations in the low-affinity p...

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Bibliographic Details
Main Authors: Xinglin Zhang, Fernanda L Paganelli, Damien Bierschenk, Annemarie Kuipers, Marc J M Bonten, Rob J L Willems, Willem van Schaik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3386183?pdf=render