BRCA Genetic Screening in Middle Eastern and North African: Mutational Spectrum and Founder BRCA1 Mutation (c.798_799delTT) in North African

Background. The contribution of BRCA1 mutations to both hereditary and sporadic breast and ovarian cancer (HBOC) has not yet been thoroughly investigated in MENA. Methods. To establish the knowledge about BRCA1 mutations and their correlation with the clinical aspect in diagnosed cases of HBOC in ME...

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Main Authors: Abdelilah Laraqui, Nancy Uhrhammer, Hicham EL Rhaffouli, Yassine Sekhsokh, Idriss Lahlou-Amine, Tahar Bajjou, Farida Hilali, Jamila El Baghdadi, Abderrahmane Al Bouzidi, Youssef Bakri, Said Amzazi, Yves-Jean Bignon
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2015/194293