How to normalize metatranscriptomic count data for differential expression analysis
Background Differential expression analysis on the basis of RNA-Seq count data has become a standard tool in transcriptomics. Several studies have shown that prior normalization of the data is crucial for a reliable detection of transcriptional differences. Until now it has not been clear whether an...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2017-10-01
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Series: | PeerJ |
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Online Access: | https://peerj.com/articles/3859.pdf |