Metabolomic profiling of rare cell populations isolated by flow cytometry from tissues

Little is known about the metabolic regulation of rare cell populations because most metabolites are hard to detect in small numbers of cells. We previously described a method for metabolomic profiling of flow cytometrically isolated hematopoietic stem cells (HSCs) that detects 60 metabolites in 10,...

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Bibliographic Details
Main Authors: Andrew W DeVilbiss, Zhiyu Zhao, Misty S Martin-Sandoval, Jessalyn M Ubellacker, Alpaslan Tasdogan, Michalis Agathocleous, Thomas P Mathews, Sean J Morrison
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-01-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/61980