Structural basis of inhibition of a transporter from Staphylococcus aureus, NorC, through a single-domain camelid antibody

Structural basis of inhibition of a transporter from Staphylococcus aureus, NorC, through a single-domain camelid antibody

Sushant Kumar et. al. report the 3.6 Å resolution crystal structure of NorC, a 14-transmembrane major facilitator superfamily member that is implicated in fluoroquinolone resistance in drug-resistant Staphylococcus aureus strains. The NorC structure was determined in complex with a single-domain cam...

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Bibliographic Details
Main Authors: Sushant Kumar, Arunabh Athreya, Ashutosh Gulati, Rahul Mony Nair, Ithayaraja Mahendran, Rakesh Ranjan, Aravind Penmatsa
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02357-x

Internet

https://doi.org/10.1038/s42003-021-02357-x

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