Reappearance from Obscurity: Mammalian Rad52 in Homologous Recombination

Reappearance from Obscurity: Mammalian Rad52 in Homologous Recombination

Homologous recombination (HR) plays an important role in maintaining genomic integrity. It is responsible for repair of the most harmful DNA lesions, DNA double-strand breaks and inter-strand DNA cross-links. HR function is also essential for proper segregation of homologous chromosomes in meiosis,...

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Bibliographic Details
Main Authors: Kritika Hanamshet, Olga M. Mazina, Alexander V. Mazin
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:Genes
Subjects:
genetic recombination
DNA double-strand break repair
DNA strand exchange
BRCA1
BRCA2
RAD51
synthetic lethality
Online Access:http://www.mdpi.com/2073-4425/7/9/63

Internet

http://www.mdpi.com/2073-4425/7/9/63

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