Protein tyrosine phosphatase receptor type E (PTPRE) regulates the activation of wild-type KIT and KIT mutants differently

Protein tyrosine phosphatase receptor type E (PTPRE) regulates the activation of wild-type KIT and KIT mutants differently

Activation of receptor tyrosine kinases needs tight control by tyrosine phosphatases to keep their normal function. In this study, we investigated the regulation of activation of the type III receptor tyrosine kinase KIT by protein tyrosine phosphatase receptor type E (PTPRE). We found that PTPRE ca...

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Bibliographic Details
Main Authors: Shaoting Zhang, Liangying Zhang, Zongying Jiang, Yue Guo, Hui Zhao, Jianmin Sun
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Biochemistry and Biophysics Reports
Subjects:
KIT
PTPRE
GISTs
Mastocytosis
Mutation
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580821000686

Internet

http://www.sciencedirect.com/science/article/pii/S2405580821000686

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