A synthetic model of human beta-thalassemia erythropoiesis using CD34+ cells from healthy adult donors.

A synthetic model of human beta-thalassemia erythropoiesis using CD34+ cells from healthy adult donors.

Based upon the lack of clinical samples available for research in many laboratories worldwide, a significant gap exists between basic and clinical studies of beta-thalassemia major. To bridge this gap, we developed an artificially engineered model for human beta thalassemia by knocking down beta-glo...

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Bibliographic Details
Main Authors: Y Terry Lee, Ki Soon Kim, Colleen Byrnes, Jaira F de Vasconcellos, Seung-Jae Noh, Antoinette Rabel, Emily R Meier, Jeffery L Miller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3704632?pdf=render

Internet

http://europepmc.org/articles/PMC3704632?pdf=render

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