Comparison of apoA-I helical structure and stability in discoidal and spherical HDL particles by HX and mass spectrometry

Comparison of apoA-I helical structure and stability in discoidal and spherical HDL particles by HX and mass spectrometry

Elucidation of apoA-I secondary structure in spherical plasma HDL particles is essential for understanding HDL structure and function at the molecular level. To provide this information, we have applied hydrogen exchange (HX) and mass spectrometry methods to compare apoA-I secondary structure in dis...

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Bibliographic Details
Main Authors: Palaniappan Sevugan Chetty, David Nguyen, Margaret Nickel, Sissel Lund-Katz, Leland Mayne, S.Walter Englander, Michael C. Phillips
Format: Article
Language:English
Published: Elsevier 2013-06-01
Series:Journal of Lipid Research
Subjects:
amphipathic α-helix
cholesterol
lipoprotein
phospholipid
hydrogen exchange
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520357151

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http://www.sciencedirect.com/science/article/pii/S0022227520357151

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