Repetitive recombinant human bone morphogenetic protein 2 injections improve the callus microarchitecture and mechanical stiffness in a sheep model of distraction osteogenesis

Repetitive recombinant human bone morphogenetic protein 2 injections improve the callus microarchitecture and mechanical stiffness in a sheep model of distraction osteogenesis

Evidence suggests that recombinant human bone morphogenetic protein 2 (rhBMP-2) increases the mechanical integrity of callus tissue during bone healing. This effect may be either explained by an increase of callus formation or a modification of the trabecular microarchitecture. Therefore the purpose...

Full description

Bibliographic Details
Main Authors: Marc-Frederic Pastor, Thilo Floerkemeier, Frank Witte, Jens Nellesen, Fritz Thorey, Henning Windhagen, Mathias Wellmann
Format: Article
Language:English
Published: Open Medical Publishing 2012-03-01
Series:Orthopedic Reviews
Subjects:
bone morphogenetic protein (BMP), Modeling and remodeling, Microcomputed Tomography (μCT), load bearing capacity
Online Access:http://www.pagepress.org/journals/index.php/or/article/view/3963

Internet

http://www.pagepress.org/journals/index.php/or/article/view/3963

Similar Items