Nickel Sensitivity Is Associated with GH-IGF1 Axis Impairment and Pituitary Abnormalities on MRI in Overweight and Obese Subjects

Nickel Sensitivity Is Associated with GH-IGF1 Axis Impairment and Pituitary Abnormalities on MRI in Overweight and Obese Subjects

Nickel (Ni) is a ubiquitous metal, the exposure of which is implied in the development of contact dermatitis (nickel allergic contact dermatitis (Ni-ACD)) and Systemic Ni Allergy Syndrome (SNAS), very common among overweight/obese patients. Preclinical studies have linked Ni exposure to abnormal pro...

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Bibliographic Details
Main Authors: Renata Risi, Simonetta Masieri, Eleonora Poggiogalle, Mikiko Watanabe, Alessandra Caputi, Rossella Tozzi, Elena Gangitano, Davide Masi, Stefania Mariani, Lucio Gnessi, Carla Lubrano
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
obesity
nickel sensitivity
growth hormone deficiency
pituitary morphology
Online Access:https://www.mdpi.com/1422-0067/21/24/9733

Internet

https://www.mdpi.com/1422-0067/21/24/9733

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