miR-212 and miR-132 Are Downregulated in Neurally Derived Plasma Exosomes of Alzheimer’s Patients

miR-212 and miR-132 Are Downregulated in Neurally Derived Plasma Exosomes of Alzheimer’s Patients

It was recently discovered that brain cells release extracellular vesicles (EV) which can pass from brain into blood. These findings raise the possibility that brain-derived EV’s present in blood can be used to monitor disease processes occurring in the cerebrum. Since the levels of certain micro-RN...

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Bibliographic Details
Main Authors: Diana J. Cha, David Mengel, Maja Mustapic, Wen Liu, Dennis J. Selkoe, Dimitrios Kapogiannis, Douglas Galasko, Robert A. Rissman, David A. Bennett, Dominic M. Walsh
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Neuroscience
Subjects:
blood biomarker
extracellular vesicles
L1CAM
micro-RNA
mild cognitive impairment
qRT-PCR
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.01208/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2019.01208/full

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