Heparan sulfate is an important mediator of Ebola virus infection in polarized epithelial cells

Heparan sulfate is an important mediator of Ebola virus infection in polarized epithelial cells

Abstract Background Currently, no FDA-approved vaccines or treatments are available for Ebola virus disease (EVD), and therapy remains largely supportive. Ebola virus (EBOV) has broad tissue tropism and can infect a variety of cells including epithelial cells. Epithelial cells differ from most other...

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Bibliographic Details
Main Authors: Manasi Tamhankar, Dawn M. Gerhardt, Richard S. Bennett, Nicole Murphy, Peter B. Jahrling, Jean L. Patterson
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Virology Journal
Subjects:
Ebola virus
Caco-2
Polarized cells
Heparan sulfate
Online Access:http://link.springer.com/article/10.1186/s12985-018-1045-0

Internet

http://link.springer.com/article/10.1186/s12985-018-1045-0

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