Mitotane (op’DDD) restores growth and puberty in nine children with Cushing’s disease

To investigate whether low-dose mitotane (up to 2 g/day) could be a temporary therapeutic alternative to transsphenoidal surgery (TSS) in pediatric Cushing’s disease (CD). Twenty-eight patients with CD aged 12.2 years (± 2.2) were referred to our center. We compared nine patients treated with mitota...

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Bibliographic Details
Main Authors: Emmanuelle Motte, Anya Rothenbuhler, Stephan Gaillard, Najiba Lahlou, Cécile Teinturier, Régis Coutant, Agnès Linglart
Format: Article
Language:English
Published: Bioscientifica 2018-11-01
Series:Endocrine Connections
Subjects:
Online Access:https://ec.bioscientifica.com/view/journals/ec/7/12/EC-18-0215.xml