Production of Lentiviral Vectors Encoding Recombinant Factor VIII Expression in Serum-Free Suspension Cultures

ABSTRACT Lentiviral vector-mediated gene transfer offers several advantages over other gene delivery vectors when considering gene and cell therapy applications. However, using these therapies in clinical applications involves large-scale vector production in an efficient and cost-effective manner....

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Bibliographic Details
Main Authors: Angelo Luis Caron, Virgínia Picanço-Castro, Sven Ansorge, Dimas Tadeu Covas, Amine Kamen, Kamilla Swiech
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2015-12-01
Series:Brazilian Archives of Biology and Technology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132015000600923&lng=en&tlng=en