Anti-Epidermal Growth Factor Receptor (EGFR) Antibodies Overcome Resistance of Ovarian Cancer Cells to Targeted Therapy and Natural Cytotoxicity

Anti-Epidermal Growth Factor Receptor (EGFR) Antibodies Overcome Resistance of Ovarian Cancer Cells to Targeted Therapy and Natural Cytotoxicity

The poor outcome of advanced ovarian cancer under conventional therapy stimulated the exploration of new strategies to improve therapeutic efficacy. In our preclinical in vitro study we investigated a combination of targeted therapy and immunotherapy. Combination treatment with the anti-EGFR-antibod...

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Bibliographic Details
Main Authors: Mahavir Singh, Sven Brandau, Nina Gottschalk, Stephan Lang, Rainer Kimmig
Format: Article
Language:English
Published: MDPI AG 2012-09-01
Series:International Journal of Molecular Sciences
Subjects:
ovarian cancer
NK cell
cetuximab
EGFR
PstS-1
antibody-dependent cellular cytotoxicity
Online Access:http://www.mdpi.com/1422-0067/13/9/12000

Internet

http://www.mdpi.com/1422-0067/13/9/12000

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