PRMT5 promotes progression of endometrioid adenocarcinoma via ERα and cell cycle signaling pathways

PRMT5 promotes progression of endometrioid adenocarcinoma via ERα and cell cycle signaling pathways

Abstract Protein arginine methyltransferase 5 (PRMT5) has previously been reported to be upregulated in many malignant tumors. This study investigated the significance of PRMT5 in endometrial carcinoma (EC) and explored its function in tumorigenesis. Immunohistochemistry was performed to evaluate PR...

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Bibliographic Details
Main Authors: Shuyu Mei, Shuang Ge, Jun Wang, Hailing Li, Xiaotong Jing, Ke Liang, Xiaoying Zhang, Chaoshuai Xue, Cuijuan Zhang, Tingguo Zhang
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:The Journal of Pathology: Clinical Research
Subjects:
endometrial cancer
epigenetics
PRMT5
ERα
cell function
Online Access:https://doi.org/10.1002/cjp2.194

Internet

https://doi.org/10.1002/cjp2.194

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