Applications of CRISPR/Cas9 in the Synthesis of Secondary Metabolites in Filamentous Fungi

Applications of CRISPR/Cas9 in the Synthesis of Secondary Metabolites in Filamentous Fungi

Filamentous fungi possess the capacity to produce a wide array of secondary metabolites with diverse biological activities and structures, such as lovastatin and swainsonine. With the advent of the post-genomic era, increasing amounts of cryptic or uncharacterized secondary metabolite biosynthetic g...

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Bibliographic Details
Main Authors: Chunmiao Jiang, Gongbo Lv, Yayi Tu, Xiaojie Cheng, Yitian Duan, Bin Zeng, Bin He
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Microbiology
Subjects:
CRISPR-Cas9
genome editing
secondary metabolites
filamentous fungi
CRISPRa
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.638096/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2021.638096/full

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