Analysis of GWAS-Derived Schizophrenia Genes for Links to Ischemia-Hypoxia Response of the Brain

Analysis of GWAS-Derived Schizophrenia Genes for Links to Ischemia-Hypoxia Response of the Brain

Obstetric complications (OCs) can induce major adverse conditions for early brain development and predispose to mental disorders, including schizophrenia (SCZ). We previously hypothesized that SCZ candidate genes respond to ischemia-hypoxia as part of OCs which impacts neurodevelopment. We here test...

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Bibliographic Details
Main Authors: Rainald Schmidt-Kastner, Sinan Guloksuz, Thomas Kietzmann, Jim van Os, Bart P. F. Rutten
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Psychiatry
Subjects:
schizophrenia
gene-environment (G-E) interaction
obstetric complications
ischemia
hypoxia
HIF
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2020.00393/full

Internet

https://www.frontiersin.org/article/10.3389/fpsyt.2020.00393/full

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