Epigenetic regulation of placental gene expression in transcriptional subtypes of preeclampsia

Epigenetic regulation of placental gene expression in transcriptional subtypes of preeclampsia

Abstract Background Preeclampsia (PE) is a heterogeneous, hypertensive disorder of pregnancy, with no robust biomarkers or effective treatments. We hypothesized that this heterogeneity is due to the existence of multiple subtypes of PE and, in support of this hypothesis, we recently identified five...

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Bibliographic Details
Main Authors: Katherine Leavey, Samantha L. Wilson, Shannon A. Bainbridge, Wendy P. Robinson, Brian J. Cox
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Clinical Epigenetics
Subjects:
Preeclampsia
Placenta
DNA methylation
Gene expression
Clustering
Subtypes
Online Access:http://link.springer.com/article/10.1186/s13148-018-0463-6

Internet

http://link.springer.com/article/10.1186/s13148-018-0463-6

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