MicroRNAs modulate the dynamics of the NF-κB signaling pathway.

NF-κB, a major transcription factor involved in mammalian inflammatory signaling, is primarily involved in regulation of response to inflammatory cytokines and pathogens. Its levels are tightly regulated since uncontrolled inflammatory response can cause serious diseases. Mathematical models have be...

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Bibliographic Details
Main Authors: Candida Vaz, Arvind Singh Mer, Alok Bhattacharya, Ramakrishna Ramaswamy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3219691?pdf=render