Genetic interaction mapping with microfluidic-based single cell sequencing.

Genetic interaction mapping is useful for understanding the molecular basis of cellular decision making, but elucidating interactions genome-wide is challenging due to the massive number of gene combinations that must be tested. Here, we demonstrate a simple approach to thoroughly map genetic intera...

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Bibliographic Details
Main Authors: John R Haliburton, Wenjun Shao, Adam Deutschbauer, Adam Arkin, Adam R Abate
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5295688?pdf=render