The Fanconi Anemia Pathway of Genomic Maintenance

Fanconi anemia (FA), a recessive syndrome with both autosomal and X-linked inheritance, features diverse clinical symptoms, such as progressive bone marrow failure, hypersensitivity to DNA cross-linking agents, chromosomal instability and susceptibility to cancer. At least 12 genetic subtypes have b...

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Bibliographic Details
Main Authors: Marieke Levitus, Hans Joenje, Johan P. de Winter
Format: Article
Language:English
Published: Hindawi Limited 2006-01-01
Series:Cellular Oncology
Online Access:http://dx.doi.org/10.1155/2006/974975