Overexpression of PD-1 on Peripheral Blood Lymphocytes in Patients with Idiopathic Pulmonary Arterial Hypertension and Its Association with High Viral Loads of Epstein-Barr Virus and Poor Clinical Parameters

Overexpression of PD-1 on Peripheral Blood Lymphocytes in Patients with Idiopathic Pulmonary Arterial Hypertension and Its Association with High Viral Loads of Epstein-Barr Virus and Poor Clinical Parameters

Idiopathic pulmonary arterial hypertension (IPAH) is a rare but severe disease with the elevated blood pressure in the pulmonary arteries without a known trigger of vascular remodelling. It leads to the right heart failure with reduced survival. Changes in the immunological landscape of the lungs an...

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Bibliographic Details
Main Authors: Michał Tomaszewski, Ewelina Grywalska, Andrzej Tomaszewski, Piotr Błaszczak, Marcin Kurzyna, Jacek Roliński, Grzegorz Kopeć
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Journal of Clinical Medicine
Subjects:
idiopathic pulmonary arterial hypertension
IPAH
cardiovascular disease
Epstein–Barr virus
EBV
PD-1
Online Access:https://www.mdpi.com/2077-0383/9/6/1966

Internet

https://www.mdpi.com/2077-0383/9/6/1966

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