Insulin-like growth factor II prevents oxidative and neuronal damage in cellular and mice models of Parkinson's disease

Insulin-like growth factor II prevents oxidative and neuronal damage in cellular and mice models of Parkinson's disease

Oxidative distress and mitochondrial dysfunction, are key factors involved in the pathophysiology of Parkinson's disease (PD). The pleiotropic hormone insulin-like growth factor II (IGF-II) has shown neuroprotective and antioxidant effects in some neurodegenerative diseases. In this work, we de...

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Bibliographic Details
Main Authors: Elisa Martín-Montañez, Nadia Valverde, David Ladrón de Guevara-Miranda, Estrella Lara, Yanina S. Romero-Zerbo, Carmelo Millon, Federica Boraldi, Fabiola Ávila-Gámiz, Ana M. Pérez-Cano, Pablo Garrido-Gil, Jose Luis Labandeira-Garcia, Luis J. Santin, Jose Pavia, Maria Garcia-Fernandez
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Redox Biology
Subjects:
Insulin like growth factor-II
Neuroprotection
Mitochondria
Oxidative distress
Parkinson's disease
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231721002548

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http://www.sciencedirect.com/science/article/pii/S2213231721002548

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