Consistent inverse correlation between DNA methylation of the first intron and gene expression across tissues and species

Consistent inverse correlation between DNA methylation of the first intron and gene expression across tissues and species

Abstract Background DNA methylation is one of the main epigenetic mechanisms for the regulation of gene expression in eukaryotes. In the standard model, methylation in gene promoters has received the most attention since it is generally associated with transcriptional silencing. Nevertheless, recent...

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Bibliographic Details
Main Authors: Dafni Anastasiadi, Anna Esteve-Codina, Francesc Piferrer
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Epigenetics & Chromatin
Subjects:
DNA methylation
Gene expression
First intron
Regulation
Gene features
Online Access:http://link.springer.com/article/10.1186/s13072-018-0205-1

Internet

http://link.springer.com/article/10.1186/s13072-018-0205-1

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