Fat body Ire1 regulates lipid homeostasis through the Xbp1s-FoxO axis in Drosophila

Fat body Ire1 regulates lipid homeostasis through the Xbp1s-FoxO axis in Drosophila

Summary: The endoplasmic reticulum (ER)-resident transmembrane protein kinase/RNase Ire1 is a conserved sensor of the cellular unfolded protein response and has been implicated in lipid homeostasis, including lipid synthesis and transport, across species. Here we report a novel catabolic role of Ire...

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Bibliographic Details
Main Authors: Peng Zhao, Ping Huang, Tongfu Xu, Xiaoxiang Xiang, Ying Sun, Jingqi Liu, Cheng Yan, Lei Wang, Jiamei Gao, Shang Cui, Xiangdong Wang, Lixing Zhan, Haiyun Song, Jingnan Liu, Wei Song, Yong Liu
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:iScience
Subjects:
Lipid
Molecular biology
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221007872

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http://www.sciencedirect.com/science/article/pii/S2589004221007872

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