Enhanced protection against Ebola virus mediated by an improved adenovirus-based vaccine.

The Ebola virus is transmitted by direct contact with bodily fluids of infected individuals, eliciting death rates as high as 90% among infected humans. Currently, replication defective adenovirus-based Ebola vaccine is being studied in a phase I clinical trial. Another Ebola vaccine, based on an at...

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Bibliographic Details
Main Authors: Jason S Richardson, Michel K Yao, Kaylie N Tran, Maria A Croyle, James E Strong, Heinz Feldmann, Gary P Kobinger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2669164?pdf=render