A viral microRNA down-regulates multiple cell cycle genes through mRNA 5'UTRs.

A viral microRNA down-regulates multiple cell cycle genes through mRNA 5'UTRs.

Global gene expression data combined with bioinformatic analysis provides strong evidence that mammalian miRNAs mediate repression of gene expression primarily through binding sites within the 3' untranslated region (UTR). Using RNA induced silencing complex immunoprecipitation (RISC-IP) techni...

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Bibliographic Details
Main Authors: Finn Grey, Rebecca Tirabassi, Heather Meyers, Guanming Wu, Shannon McWeeney, Lauren Hook, Jay A Nelson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20585629/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20585629/?tool=EBI

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