Overexpression of RNF146 in non-small cell lung cancer enhances proliferation and invasion of tumors through the Wnt/β-catenin signaling pathway.

Overexpression of RNF146 in non-small cell lung cancer enhances proliferation and invasion of tumors through the Wnt/β-catenin signaling pathway.

Studies have suggested a possible correlation between the newly identified E3 ubiquitin ligase ring finger protein 146 (RNF146) and tumor development. However, until now, studies on RNF146 have been restricted to poly(ADP-ribosyl)ation and ubiquitin ligation, whereas the role of RNF146 in tumor biol...

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Bibliographic Details
Main Authors: Ying Gao, Chengyang Song, Linping Hui, Chun-yu Li, Junying Wang, Ye Tian, Xu Han, Yong Chen, Da-Li Tian, Xueshan Qiu, Enhua Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3891871?pdf=render

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http://europepmc.org/articles/PMC3891871?pdf=render

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